Thursday, May 24, 2012

1112.2066 (Elena Agliari et al.)

Organization and evolution of synthetic idiotypic networks    [PDF]

Elena Agliari, Lorenzo Asti, Adriano Barra, Luca Ferrucci
We introduce a class of weighted graphs whose properties are meant to mimic the topological features of idiotypic networks, namely the interaction networks involving the B-core of the immune system. Each node is endowed with a bit-string representing the idiotypic specificity of the corresponding B cell and a proper distance between any couple of bit-strings provides the coupling strength between the two nodes. We show that a biased distribution of the entries in bit-strings can yield fringes in the (weighted) degree distribution, small-worlds features, and scaling laws, in agreement with experimental findings. We also investigate the role of ageing, thought of as a progressive increase in the degree of bias in bit-strings, and we show that it can possibly induce mild percolation phenomena, which are investigated too.
View original: http://arxiv.org/abs/1112.2066

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